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Arterial Plaque Reduced with High Doses of Cholesterol-Lowering Statin

Posted on Nov 29, 2011

November 29, 2011 –According to Medline Plus, arterial plaque is found to be reduced with high doses of cholesterol-lowering statins such as Lipitor and Crestor. In addition, the progression of coronary artery disease was reversed.

A 2-year-study involving 1,385 patients revealed a 1.22 percent reduction of arterial plaque when taking Crestor and a 0.99 percent reduction with Lipitor. High doses were considered to be 40 mg of Crestor and 80 mg of Lipitor.

In the patients who took Lipitor, 64.7 percent of them experienced a reduction in arterial plaque. In those who took Crestor, 71.3% of the patients experienced the same.

All of the patients had coronary angiography performed, due to abnormal findings on a stress test or chest pain. In previous studies, patients under similar circumstances were taking lower doses of statins. The risk of suffering a stroke or heart attack, or the need for angioplasty was between 15 to 20 percent. Rates were less than half of that for patients in this study taking higher doses of statins.

Although doctors are cautious about prescribing higher doses of statins, researchers indicate that the benefits were greater than any risks and that no side effects were experienced.

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